Careers

Neoleukin Therapeutics is recruiting motivated individuals with biotechnology experience throughout our organization. Specific employment opportunities are posted below.

Neoleukin Therapeutics is proud to be an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status, or age, and Neoleukin will not tolerate discrimination or harassment based on any of the above characteristics.

Applications can be submitted to careers@neoleukin.com


Research Interns

Neoleukin Therapeutics is seeking exceptional interns to join our Research and Development team for the summer! If you are a current student working towards your MS or PhD in the fields of Life Sciences and/or Computer Science and share our passion for improving lives, please apply!

Start Date: Summer 2019, Flexible.
Length of Assignment: 12-16 weeks.
Work Hours: 40 hours per week.

The mission of Neoleukin Therapeutics is to develop breakthrough de novo protein therapeutics. This paid internship will focus on the development of de novo proteins and/or computational tools for protein engineering. The intern will have the opportunity to gain experience in a variety experimental and scientific fields, including biochemistry, molecular biology, cell biology, and computer science.

Only a few spots are available for this unique opportunity, and thus we encourage early applications.


Post-doctoral Fellows

Post-doctoral fellows will focus on de novo engineering of novel protein-based therapies using a combination of computational and experimental approaches. The selected candidates will work for one to two years on a predetermined aspect of de novo protein design of cell-signaling molecules.

The scientist will work closely with a multidisciplinary team and have the opportunity to interface with basic-research, pre-clinical development, and clinical applications.

Responsibilities:

  • Implementation of team goals

  • Protein design/engineering, production, and characterization

  • Preparation of data summaries, reports, manuscripts and presentations of research results.

  • Together with administrative management, ensure the implementation and adherence to all applicable safety, stewardship, and other legal requirements.

  • Building an effective collaborative network within Neoleukin Therapeutics, its research partners and leading experts in academia and industry.

Qualifications:

  • Ph.D. in Biochemistry, Computer Science, Chemical Engineering, Systems/or/Synthetic Biology, or related fields.

  • Proven exceptional record of research, including high-impact peer-reviewed publications on international journals.

  • Strong written and oral communication and presentation skills

  • Ability to work in a team environment encompassing multiple disciplines

  • Experience in Protein Biochemistry, Protein Engineering, and/or computer science applied to biological systems.

Preferred Qualifications:

  • Expertise in Biochemistry, protein characterization, protein chemistry (small molecules and non-canonical amino acids are a plus), computer science (machine-learning is a plus), liquid chromatography and mass spectrometry.


Research Associate

The ideal candidate will be highly organized, self-directed, willing to learn, able to multi-task, and have excellent communication and problem-solving skills.

Responsibilities:

  • Execution, optimization and troubleshooting of preestablished experimental designs

  • Expression and purification of recombinant proteins from various cell types (bacterial, yeast, insect, mammalian)

  • Characterization of biological molecules using analytical and biochemical assays

  • Performance of a wide variety of standard molecular and cell biology techniques, including protein binding assays, cell-based assays and cell culture

  • Partnering with our R&D groups to maintain and expand our de novo protein portfolio

  • Assisting with laboratory setup and maintenance duties

  • Organization and documentation of methods and results

Qualifications:

  • BS, MS (or PhD) in biological sciences (Biochemistry, Bioengineering, Cell Biology, Chemistry, Molecular Biology or a related field)

  • 1-5 years industry experience

  • Demonstrated experience in bacteria and yeast culture and sterile techniques

  • Experience performing SDS-PAGE required

  • General knowledge of Molecular Biology, including SDS-PAGE, Western blots and ELISA

  • Experience in protein chemistry, molecular biology, and/or analytical biochemistry

  • Experience with protein expression and purification techniques in microbial and mammalian systems is a plus

  • Experience with small to medium scale production, including bioreactor systems, and recombinant protein manufacture is a plus

  • Ability to problem solve and identify work to be done pro-actively

  • Attention to detail and strong work ethic

  • Excellent written and oral communication skills

  • Highest level of integrity


Laboratory Manager

The laboratory manager candidate will join our Research and Development team and support our lab as we research and develop programs in de novo design of protein immunotherapeutics.

In collaboration with senior management, the candidate will be responsible for designing and managing the function and upkeep of the laboratory, laboratory equipment and supplies. As a startup looking to develop an inspiring work environment, Neoleukin embraces a collaborative and team-based approach.

Responsibilities:

  • Primary point-of-contact for all laboratory-related activities.

  • Partner with cross-functional teams including R&D, Operations, Project Management, Facilities, Quality and Regulatory in a research and clinical setting.

  • Perform supply chain logistics which includes forecasting and procuring materials for R&D demand and inventory control, and maintaining communications with vendor representatives.

  • Manage laboratory day-to-day operations including lab organization (5S), laboratory facilities, lab accessibility and security, and safety protocols.

  • Ensure adherence to regulatory and quality requirements to be in compliance with lab regulations and certifications.

  • Perform lab asset management duties including maintaining instrument calibrations, servicing laboratory equipment, and managing equipment and asset database.

  • Maintain a clean and organized working environment for researchers to conduct experiments.

Qualifications:

  • Bachelor’s degree in Biochemistry, Chemistry or related fields in Life Sciences.

  • Minimum of 2 years experience working in an academic or commercial research lab.

  • Knowledge of lab protocols, equipment and supplies in molecular biology, protein expression/purification/characterization, tissue culture, and process development.

  • Experience in a regulated Clinical or Quality laboratory environment is a plus.

  • Candidate will have basic knowledge and training in working in a biosafety 2 lab environment.

  • Able to work independently and in coordination with R&D, Operations, and Quality teams.

  • Experience running projects with multi-functional teams while adhering to tight deadlines in a fast-paced environment.

  • Excellent attention to detail and ability to maintain a high level of accuracy in record keeping and documentation.

  • Strong organizational skills required.

  • Able to communicate at all levels of the organization including managers and senior leaders in the organization.

  • Strong written and oral communication skills.

  • Ability to work in a team environment encompassing multiple disciplines with excellent interpersonal and management skills.

  • Must be able to lift 35 lbs.


Scientist/Senior Scientist, De Novo Protein Design

Neoleukin Therapeutics is seeking an exceptional scientist to lead research programs in de novo design of protein therapeutics at the level of Scientist or Senior Scientist, depending on experience level. The focus will be the de novo engineering of novel protein-based therapies, using a combination of computational and experimental approaches. The scope will include multiple aspects of de novo protein design, and targets will include cytokines, cell-signaling molecules, and other key immune- modulating or metabolic targets.

The selected scientist will be responsible for designing and managing research programs in collaboration with senior management to translate our high-level strategic vision into scientific reality. As a startup looking to develop an inspiring work environment, Neoleukin embraces a collaborative and team-based approach. If you are a resourceful, tenacious, and flexible scientist with excellent knowledge in computational protein design, then you may be an ideal candidate.

Responsibilities:

  • Determination and implementation of team goals

  • Use of existing computational tools for protein engineering

  • Development of new computational tools for de novo protein design/engineering

  • Biochemical and biophysical experimental characterization of designed proteins

  • Preparation of data summaries, reports, manuscripts, and presentations of research results

  • Direct efforts to build an active and collaborative network within Neoleukin Therapeutics, with its research partners as well as with leading experts in academia and industry

  • Lead a team of researchers while interfacing with senior management regularly

  • In partnership with administrative management, the candidate will also be responsible for the implementation of and adherence to all applicable safety, stewardship, and other legal requirements.

Qualifications:

  • Ph.D. in Biochemistry, Chemistry, Computer Science, Systems/or/Synthetic Biology, or related fields in Life Sciences and/or computer science.

  • Expertise in biological systems and modeling of proteins/macromolecules. At least 2-years of postdoctoral or biotech industry experience.

  • Proven exceptional record of research, including peer-reviewed publications in international journals.

  • Demonstrated experience in Computational Protein Engineering, Protein Structure Prediction, Protein Biochemistry, and/or Computer Science applied to Protein Engineering.

  • Fluent in Linux, and programming in C/C++/MPI, Python, BASH (other languages are a plus). Experience using Rosetta++ is highly desirable.

  • Excellent written and oral communication and presentation skills.

  • Ability to work in a team environment encompassing multiple disciplines with excellent interpersonal and management skills.